Nano News
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Nanolive technology highlights the importance of wnt signaling in organoid self-organization
Cell-cell interactions between embryonic stem cells (ESCs) and trophoblast stem cells (TSCs) play a vital role in tissue formation in developing embryos [1]. The two cell types are known to communicate through the wnt/β-catenin signaling pathway [2], but identifying...
Bioenergetics Consequences of Mitochondrial Transplantation in Cardiomyocytes
Could Mitochondrial transplantation into Cardiomyocytes be an effective treatment for cardiac disease? This paper shows the first test of transplanting non-autologous mitochondria from healthy skeletal muscle cells into normal cardiomyocytes. This transplant led to...
Marker-free visualization of fibrin network formation by MDA-MB-231 cells
The main event in blood coagulation is fibrin network formation as a result of the polymerization of the soluble plasma protein fibrinogen [1]. Alterations in this process lead to hemostatic and thrombotic disorders such as hemophilia [2] or thrombosis [3]....
Neutrophils are mediators of metastatic prostate cancer progression in bone
Nanolive is proud to share a new publication in Cancer Immunology, Immunotherapy (2020) from users of the 3D Cell Explorer at the Department of Pathology and Microbiology of the University of Nebraska Medical Center in the United States [1].Costanzo-Garvey and...
New webinar: Characterization of Stem cell differentiation dynamics with label-free live cell imaging
We are happy to invite you to watch our recorded webinar that was aired on March 24th and 25th 2020. Please register here to view the webinar on-demand:In this webinar, Dr. Emma Gibbin, Communications Specialist at Nanolive will: discuss the unique challenges that...
Molecular heterogeneity in breast carcinoma cells with increased invasive capacities
Nanolive is happy to share a new publication in Radiology and Oncology, from users of the 3D Cell Explorer at the Medical University of Innsbruck, in Austria [1].To date, one of the challenges in breast cancer clinical oncology is its metastatic progression, which is...
Pneumonia bacteria phagocyted by neutrophils
In this unique label-free footage obtained from a demo at the Infection and Immunity lab of the UMC in Utrecht, a culture of neutrophils can be seen phagocyting pneumonia bacteria. An image was obtained every 1.9s for 4 minutes and 45 seconds. We can clearly...
Feature Client: Gabriel Ichim from the Centre for Cancer Research (CRCL) in Lyon, France
Gabriel is one of 500 researchers currently based at the Centre for Cancer Research (CRCL) in Lyon, France. He created his lab “Cancer Cell Death” in October 2016 and has “been having fun killing cancer cells” ever since. The focus of his lab is apoptosis, the most...
Nanolive’s Grand Opening Day
One week ago with had the great pleasure to officially open the new headquarters of Nanolive and it was a huge success. More than 100 guests came to celebrate this big day and enjoyed tours in the office and demonstrations of the Nanolive imaging microscopes. Please...
Mitochondrial trafficking in neurons
Mitochondria play an essential role in neurone function. They provide the energy and metabolites needed to: (i) form and maintain the synapses (neural junctions) that exist between cells, (ii) remove or repair old/damaged components, and (iii) deliver new materials,...
Cilia visualization in Xenopus cells
Multi-ciliated cells (MCCs) are terminally differentiated epithelia that are present in all metazoans and many unicellular eukaryotes1,2. In marine organisms they play a key role in locomotion and feeding3, while in mammals they clear mucus from the lungs, circulate...
New Publication from the Laboratory of Human Lymphohematopoiesis in Paris, France
A gain-of-function RAC2 mutation is associated with bone marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency Nanolive is happy to introduce a new publication in the Haematologica Journal of The Ferrata Storti Foundation, featuring...
New Publication from the Cancer Research Centre in Lyon, France
Caspase-8 deficiency induces a switch from TLR3-induced apoptosis to lysosomal cell death in neuroblastoma cell lines Nanolive is happy to announce a new publication from users of the 3D Cell Explorer-Fluo based at the Cancer Research Centre in Lyon, France. Evasion...
New Publication from the University of Sydney, Australia
We are happy to introduce a new publication featuring Nanolive’s 3D Cell Explorer produced by users at the University of Sydney, Australia. Understanding the mechanisms that underlie cell-cell interactions holds the key to understanding how material is transferred and...
Grand Opening of Nanolive’s new office in Tolochenaz, Switzerland
We are very proud to invite you to the Grand Opening of Nanolive's new office in Tolochenaz! Having started in a tiny office containing only a few desks back in 2013, moving to our new headquarters (1100 m2) is a huge milestone for us and it is one that we would like...
Workshop on Light Microscopy & Cellular Imaging in Life Sciences at Florida Atlantic University from 16-18 December
Nanolive is happy to invite you to our workshop at the Florida Atlantic University from December 16-18 from 9am to 5pm in the imaging facility FAU Jupiter, Cell Imaging Core. We are looking forward to meeting you there! If you need additional information or have...
Tumor-derived extracellular vesicles uptake in mouse brain endothelial cells
Tumor-associated macrophages, as mentioned in our previous post featuring mouse macrophages, secrete extracellular vesicles (EVs) that range from a variety of sizes and subcellular origins[1]–[5], and that play a role in tumor progression processes like metastasis and...
Seminar invitation at ASCB|EMBO 2019 in Washington D.C.: Automated Label-free 3D Live Cell Imaging in Drug Discovery
Nanolive will be holding a seminar on Monday, December 9th @ 2 pm in Theater 2 (abstract below) where we will present our latest live cell microscope – the CX-A – the world’s first walk-away solution for label-free, long-term live cell imaging. We would like to invite...