Scientific Publications
Peer-reviewed research using Nanolive imagingDiscover a list of peer-reviewed scientific publications using Nanolive imaging in the fields of drug discovery, cell metabolism, etc.
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Cathodoluminescence imaging of cellular structures labeled with luminescent iridium or rhenium complexes at cryogenic temperatures
Authors: Marie Vancová; Radim Skoupý; Eva Ďurinová; Tomáš Bílý; Jana Nebesářová; Vladislav Krzyžánek; Aleš Kolouch; Petr Horodyský
https://doi.org/10.1038/s41598-022-17723-w, 2022
Published in: Scientfic Reports
Tags: cathodoluminescence; iridium; rhenium
ATP synthase is essential for high conductance but not low conductance Mitochondrial Permeability Transition
Authors: M.A. Neginskaya; S.E. Morris; E.V. Pavlov
https://doi.org/10.1101/2021.11.16.468842, 2022
Published in: bioRxiv
Tags: mitochondria; ATP synthase; MTP
Mitochondrial dysfunction and epithelial to mesenchymal transition in head neck cancer cell lines
Authors: Maria do Carmo Greier; Annette Runge; Jozsef Dudas; Viktoria Pider; Ira-Ida Skvortsova; Dragana Savic; Herbert Riechelmann
https://doi.org/10.1038/s41598-022-16829-5, 2022
Published in: Scientific Reports
Tags: mitochondria; mesenchymal stem cells; head neck cancer
A cold-water polysaccharide-protein complex from Grifola frondosa exhibited antiproliferative activity via mitochondrial apoptotic and Fas/FasL pathways in HepG2 cells
Authors: Jiahui Zhao; Kaiyue Liang; Hao Zhong; Shizhu Liu; Peilong Sun; Rongjun He
https://doi.org/10.1016/j.ijbiomac.2022.07.098, 2022
Published in: International Journal of Biological Macromolecules
Tags: G. frondosa; Polysaccharide-protein complex; Cold-water extraction; Structural analysis; HepG2 cell inhibitory activity
Laminin Receptor-Mediated Nanoparticle Uptake by Tumor Cells: Interplay of Epigallocatechin Gallate and Magnetic Force at Nano–Bio Interface
Authors: Sheng-Chieh Hsu; Nian-Ping Wu; Yi-Ching Lu; Yunn-Hwa Ma
https://doi.org/10.3390/pharmaceutics14081523, 2022
Published in: Pharmaceutics
Tags: magnetic nanoparticles; endocytosis; epigallocatechin gallate; 67LR; Akt
Comparative analysis of Radachlorin accumulation, localization, and photobleaching in three cell lines by means of holographic and fluorescence microscopy
Authors: A.A. Zhikhoreva, A.V. Belashov, T.N. Belyaeva, A.V. Salova, I.K. Litvinov, E.S. Kornilova, I.V. Semenova, O.S. Vasyutinskii
https://doi.org/10.1016/j.pdpdt.2022.102973, 2022
Published in: Photodiagnosis and Photodynamic Therapy
Tags: photodynamic treatment, malignant cells, fluorescent analysis, digital holographic microscopy, phase images
Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen receptor-positive breast cancer
Authors: Johanna M. Buschhaus, Shrila Rajendran, Brock A. Humphries, Alyssa C. Cutter, Ayşe J. Muñiz, Nicholas G. Ciavattone, Alexander M. Buschhaus, Tatiana Cañeque, Zeribe C. Nwosu, Debashis Sahoo, Avinash S. Bevoor, Yatrik M. Shah, Costas A. Lyssiotis, Pradipta Ghosh, Max S. Wicha, Raphaël Rodriguez, Gary D. Luker
https://doi.org/10.1038/s41388-022-02385-9, 2022
Published in: Oncogene
Tags: breast cancer, stem cells, iron, lysosome, drug resistance, estrogen-targeted therapy
Engineering CpG-ASO-Pt-loaded macrophages (CAP@M) for synergistic chemo-/gene-/immuno-therapy
Authors: Yuqi Wang, Lingpu Zhang, Yan Liu, Linlin Tang, Juan He, Xiaqing Sun, Muhsin H. Younis, Daxiang Cui, Haihua Xiao, Dong Gao, Xiang-Yang Kong, Weibo Cai, Jie Song
https://doi.org/10.1002/adhm.202201178, 2022
Published in: Advanced Healthcare Materials
Tags: macrophages; antitumor; drug delivery; immunology; immunotherapy; nanomedicine
Feature Application: Smart Lipid Droplet Assay LIVE
In this application note, we showcase some of the potential uses of the Smart Lipid Droplet Assay (SLDA) including quantifying signs of aging in human skin cells (case study 1); investigating LD dynamics during foam macrophage formation (case study 2); examining LD dry mass dynamics in cancer cells (case study 3), and dissecting the details of LD biogenesis (case study 4).
Technical Note: Smart Lipid Droplet Assay LIVE
In this Technical Note, we introduce the Smart Lipid Droplet Assay (SLDA) and showcase its output in multiple cell types at varying confluences and across different field of view sizes. We then compare the performance of the SLDA against the fluorescence marker LipidSpot 610, before finishing with a case study where we use the SLDA to quantify how oleic acid (OA) addition changes LD dynamics in pre-adipocyte cells.