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Bioactive potential: a pharmacognostic definition through the screening of four Hypericum species from the Canary Islands

Oct 4, 2022

Authors: Rodney Lacret; Adrián Puerta; Sebastian Granica; Aday González-Bakker; Danela Hevia; Yiling Teng; Candelaria C. Sánchez-Mateo; Pedro Luis Pérez de Paz; José M. Padrón https://doi.org/10.3390/molecules27186101, 2022 Published in: Molecules Tags: Hypericum...

Preparation of a camptothecin analog FLQY2 self‑micelle solid dispersion with improved solubility and bioavailability

Sep 13, 2022

Authors: Yi Wang; Wenchao Wang; Endian Yu; Wenya Zhuang; Xuanrong Sun; Hong Wang; Qingyong Li https://doi.org/10.1186/s12951-022-01596-2, 2022 Published in: Journal of Nanobiotechnology Tags: Camptothecin, Soluplus®, Solid dispersion, Micelle, Solubility,...

Changes of cell membrane fluidity for mesenchymal stem cell spheroids on biomaterial surfaces

Sep 7, 2022

Authors: Chui-Wei Wong; Hao-Wei Han; Shan-hui Hsu https://dx.doi.org/10.4252/wjsc.v14.i8.616, 2022 Published in: World Journal of Stem Cells Tags: Cell membrane fluidity; Cell-cell interaction; Cellular spheroids; Chitosan; Hyaluronan

Early Pharmacological Profiling of Antiproliferative Compounds by Live Cell Imaging

Aug 22, 2022

Authors: Adrián Puerta; Aday González-Bakker; Guido Santos; José M. Padrón https://doi.org/10.3390/molecules27165261, 2022 Published in: Molecules Tags: phenotypic drug discovery; cancer; natural products; live cell imaging; machine learning; antimitotic drugs;...

Regulatory Programs of B-cell Activation and Germinal Center Reaction Allow B-ALL Escape from CD19 CAR T-cell Therapy

Aug 17, 2022

Authors: Nam Gyu Im; Amy Guillaumet-Adkins; Megha Wal; Anna J. Rogers; Julia Frede; Claire C. Havig; Jing Yang; Praveen Anand; Sarah K. Stegmann; Johannes M. Waldschmidt; Noori Sotudeh; Leili Niu; Jordan Voisine; Michal R. Schweiger; Clemens Grassberger; Jens G. Lohr;...
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