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Therapeutic efficacy of a synthetic brain-targeted H 2 S donor cross-linked nanomicells in ASD rats via aerobic glycolysis

Jul 8, 2024

Authors: Changmei Zhang, Lingyuan Yang, Feng Wang, Mingyuan Liu, Zehui Liu, Zibo Shen, Mingyang Zou,Lijie Wu https://doi.org/10.21203/rs.3.rs-4439170/v1, 2024 Published in: Research Square Tags: Autism spectrum disorder, Hydrogen sulfide, Cross-linked nanomicelles,...

GPR56/ADGRG1 induces biased Rho-ROCK-MLC and JAK-STAT3 signaling to promote amoeboid-like morphology and IL-6 upregulation in melanoma cells

Jun 17, 2024

Authors: Kuan-Yeh Huang, Kwai-Fong Ng, Kuan-Yu I,Yu-Chi Chang, Hsin-Yi Chen, Tse-Ching Chen, Martin Stacey, Hsi-Hsien Lin https://doi.org/10.21203/rs.3.rs-4423390/v1, 2024 Published in: Research Square Tags: adhesion GPCR, IL-6, cytoskeletal remodelling, GPR56,...

PRDX6 dictates ferroptosis sensitivity by directing cellular selenium mobilization

Jun 17, 2024

Authors: Junya Ito, Toshitaka Nakamura, Takashi Toyama, Sebastian Doll, Mirai Suzuki, Weijia Zhang, Jiashuo Zheng, Dietrich Trümbach, Naoya Yamada, Koya Ono, Adam Wahida, Yoshiro Saito, Kiyotaka Nakagawa, Eikan Mishima, Marcus Conrad...

The Glucose Transporter 5 Enhances CAR-T Cell Metabolic Function and Anti-tumour Durability

Jun 13, 2024

Authors: Bakir Valentić, Andre Kelly, Alexander A. Shestov, Zhiyang Gan, Feng Shen, Adam Chatoff, Alison Jaccard, Claudia V. Crispim, John Scholler, Simon Heeke, Nathaniel W. Snyder, Saba Ghassemi, Nicholas Jones, Saar Gill, Roddy S. O’Connor...

Correlating Protein Aggregate Structure with Cellular Function in Differentiated Muscle Cells: Discriminating Pathogenic from Non-Pathogenic Forms

Jun 13, 2024

Authors: Sander D. Mallon, Erik Bos, Vahid Sheikhhassani, Milad Shademan, Dino Rocca, Lenard M. Voortman, Alireza Mashaghi, Thomas H. Sharp, Vered Raz https://doi.org/10.1101/2024.04.25.591067, 2024 Published in: bioRxiv Tags: protein aggregates, aggregates structure,...
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