Cytotoxicity Archives

Polyalanine Expansion in PABPN1 Alters the Structure and Dynamics of Its Nuclear Aggregates in Differentiated Muscle Cells

Jun 30, 2025

Authors: Sander D. Mallon, Erik Bos, Vahid Sheikhhassani, Milad Shademan, Lenard M. Voortman, Alireza Mashaghi, Thomas H. Sharp, Vered Raz https://doi.org/10.1096/fj.202501097R Published in: FASEB Journal (2025) Tags: aggregates structure, imaging, muscle, OPMD,...

Omaveloxolone Suppresses Cell Growth and Causes Cell Cycle Arrest by Downregulating CDC20 Expression in Glioblastoma Cells Both In Vitro and In Vivo

May 30, 2025

Authors: Kuan-Ting Lee, Yi-Chiang Hsu, Ann-Shung Lieu, Chih-Lung Lin, Tai-Hsin Tsai https://doi.org/10.1111/jcmm.70607, 2025 Published in: Journal of Cellular and Molecular Medicine Tags: CDC20; cell cycle; glioblastoma; Nrf2; omaveloxolone

Yuanhuacine suppresses head and neck cancer growth by promoting ASCT2 degradation and inhibiting glutamine uptake

May 16, 2025

Authors: Xin-yi Chen, Xin Chen, Xiao-hui Liang, Dong Lu, Rong-rong Pan, Qing-yi Xiong, Xiao-xia Liu, Jia-yi Lin, Li-jun Zhang, Hong-zhuan Chen, Jin-mei Jin, Wei-dong Zhang, Xin Luan https://doi.org/10.1038/s41401-025-01562-2, 2025 Published in: Acta Pharmacologica...

The correlation of immunotoxicity with size and chemical properties of particulate matter within macrophages

May 2, 2025

Authors: Hsiang-Yu Kung, Yi-Shiuan Wang, Yung-Jui Chen, Ting-Hsuan Wu, Jai-Yu Chen, Yueh-Feng Wen, Yu-Cheng Chen, Hong-Lin Chan, Hsiu-Chuan Chou https://doi.org/10.1016/j.cbpc.2025.110215, 2025 Published in: Comparative Biochemistry and Physiology Part C: Toxicology...

Multimodal antiproliferative effects of oleanolic acid mitocans: In vitro and in vivo studies

Apr 30, 2025

Authors: Adrián Puerta, Aday González-Bakker, Eduardo Romanos, Inmaculada Aguilar Domínguez, Mónica Martínez-Montiel, Penélope Merino-Montiel, Raquel P. Herrera, M. Concepción Gimeno, José G. Fernández-Bolaños, Óscar López, José M. Padrón...

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Polyalanine Expansion in PABPN1 Alters the Structure and Dynamics of Its Nuclear Aggregates in Differentiated Muscle Cells

Omaveloxolone Suppresses Cell Growth and Causes Cell Cycle Arrest by Downregulating CDC20 Expression in Glioblastoma Cells Both In Vitro and In Vivo

Yuanhuacine suppresses head and neck cancer growth by promoting ASCT2 degradation and inhibiting glutamine uptake

The correlation of immunotoxicity with size and chemical properties of particulate matter within macrophages

Multimodal antiproliferative effects of oleanolic acid mitocans: In vitro and in vivo studies

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