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Glioblastoma targeting by water-soluble hypericin derivate HHL-PVP and photodynamic tumour killing

Apr 14, 2025

Authors: Djenana Vejzovic, Andreas Kubin, Karoline Fechter, Christina Karner, Jaana Hartmann, Thomas Ackerbauer, Branislav Radović, Gerald Ritter, Muammer Üçal, Stefan Ropele, Kariem Mahdy Ali, Mario Mischkulnig, Marlene Leoni, Bernadette Liegl-Atzwanger, Lionel...

Eating the brain – A multidisciplinary study provides new insights into the mechanisms underlying the cytopathogenicity of Naegleria fowleri

Mar 18, 2025

Authors: Ronald Malych, Filipe Folgosa, Jana Pilátová, Libor Mikeš, Vít Dohnálek, Jan Mach, Magdaléna Matějková, Vladimír Kopecký, Pavel Doležal, Robert Sutak  https://doi.org/10.1371/journal.ppat.1012995, 2025 Published in: Plos Pathogens Tags: Naegleria fowleri;...

Multifaceted Sulfonamide-Derived Thiosemicarbazones: Combining Metal Chelation and Carbonic Anhydrases Inhibition in Anticancer Therapy

Jan 30, 2025

Authors: Mónica Martínez-Montiel, Giulia Arrighi, Paloma Begines, Aday González-Bakker, Adrián Puerta, Miguel X. Fernandes, Penélope Merino-Montiel, Sara Montiel-Smith, Alessio Nocentini, Claudiu T. Supuran, José M. Padrón, José G. Fernández-Bolaños, Óscar López...

Development of Steroidal Spiro-Heterocycles Through One-Step Cyclocondensation, Their Evaluation as Antiproliferative Agents

Jan 21, 2025

Authors: Ana I. Ahuja-Casarín, Alejandra Cortes-Percino, Aday González-Bakker, Adrián Puerta, Penélope Merino-Montiel, José Luis Vega-Baez, Francisco J. Melendez, María Eugenia Castro, Óscar López, José M. Padrón, Sara Montiel-Smith...

Kremen1 dependence receptor induces SEC24C- and ATG9A-dependent 2 autophagic cell death

Jan 16, 2025

Authors: Sonia Brahim, Thomas Schott, Shiva Ghasemi, Ana Negulescu, Clara Geneste, Elisabeth Errazuriz-Cerda, Gabriel Ichim, Profile Patrick Mehlen, Olivier Meurette https://doi.org/10.1101/2025.01.15.633131, 2025 Published in: bioRxiv Tags: Cancer; cell death; ATG9A;...
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