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AI-based classification of anticancer drugs reveals nucleolar condensation as a predictor of immunogenicity

Dec 21, 2024

Authors: Giulia Cerrato, Peng Liu, Liwei Zhao, Adriana Petrazzuolo, Juliette Humeau, Sophie Theresa Schmid, Mahmoud Abdellatif, Allan Sauvat, Guido Kroemer https://doi.org/10.1186/s12943-024-02189-3, 2024 Published in: Molecular Cancer Tags: Artificial intelligence;...

Molecular mechanism of ectopic lipid accumulation induced by methylglyoxal via activation of the NRF2/PI3K/AKT pathway implicates renal lipotoxicity caused by diabetes mellitus

Oct 30, 2024

Authors: Chiung Chi Peng, Eugene Chang Yu Chen, Chang-Rong Chen, Charng-Cherng Chyau, Kuan-Chou Chen, Robert Y. Peng https://doi.org/10.1371/journal.pone.0306575, 2024 Published in: Plos One Tags: Chronic kidney disease, diabetes mellitus, lipid accumulation, renal...

T7 Peptide-modified macrophage membrane-coated nanoplatform for enhanced glioma treatment

Oct 30, 2024

Authors: Xuanrong Sun, Dehui Xie, Zhao Lou, Yujie Zhou, Ming Li, Qingyong Li, Yue Cai  https://doi.org/10.1016/j.ejpb.2024.114527, 2024 Published in: European Journal of Pharmaceutics and Biopharmaceutics Tags: Biomimetic nanoplatform, macrophage membrane, glioma...

PRDX6 dictates ferroptosis sensitivity by directing cellular selenium mobilization

Jun 17, 2024

Authors: Junya Ito, Toshitaka Nakamura, Takashi Toyama, Sebastian Doll, Mirai Suzuki, Weijia Zhang, Jiashuo Zheng, Dietrich Trümbach, Naoya Yamada, Koya Ono, Adam Wahida, Yoshiro Saito, Kiyotaka Nakagawa, Eikan Mishima, Marcus Conrad...

Pulsed electric field induces exocytosis and overexpression of MAGE antigens in melanoma

Jun 17, 2024

Authors: Wojciech Szlasa, Natalia Sauer, Dagmara Baczyńska, Marcin Ziętek, Katarzyna Haczkiewicz-Leśniak, Paweł Karpiński, Mariusz Fleszar, Paulina Fortuna, Michał J. Kulus, Aleksandra Piotrowska, Alicja Kmiecik, Agnieszka Barańska, Olga Michel, Vitalij Novickij,...
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