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Exploring Multi-Faceted Bioactivity of Aβ42 Oligomers on Diverse Bio-Substrates: Implications for Alzheimer’s Disease and Cerebral Amyloid Angiopathy

Jun 17, 2024

Authors: Chen-Ji Huang, Szu-Yi Ho, Shu-Hui Wu, Yu-Lin Wang, Guo-Chung Dong https://doi.org/10.1016/j.jtice.2024.105570, 2024 Published in: Journal of the Taiwan Institute of Chemical Engineers Tags: Charge; Hydrophobicity; Protein G; Type B gelatin; Surface plasmon...

PGC-1α loss promotes mitochondrial protein lactylation in acetaminophen-induced liver injury via the LDHB-lactate axis

Jun 13, 2024

Authors: Weilong Hong, Xue Zeng, Houping Wang, Xuxin Tan, Yu Tian, Hongtao Hu, Milad Ashrafizadeh, Gautam Sethi, He Huang, Chenyang Duan https://doi.org/10.1016/j.phrs.2024.107228, 2024 Published in: Pharmacological research Tags: PGC-1α, LDHB, Mitochondrial quality...

Differential effects of coverslip-induced hypoxia and cobalt chloride mimetic hypoxia on cellular stress, metabolism, and nuclear structure.

Jun 13, 2024

Authors: Florencia Lamela, Ronell Bologna-Molina, Felipe Parietti, Vanesa Pereira-Prado, Magdalena Millán, Alejandro Silva, Juan Llaguno, Julia Alonso, Ariel Fernández, José Sotelo-Silveira, Manoela Domingues, Miguel Arocena, Jimena Hochmann...

Optogenetically controlled inflammasome activation demonstrates two phases of cell swelling during pyroptosis

Jun 13, 2024

Authors: Julien Nadjar, Sylvain Monnier, Estelle Bastien, Anne- Laure Huber, Christiane Oddou, Léa Bardoulet, Hubert B. Leloup, Gabriel Ichim, Christophe Vanbelle, Bénédicte F. Py, Olivier Destaing, Virginie Petrilli https://doi.org/10.1126/scisignal.abn8003 , 2024...

Optogenetically controlled inflammasome activation demonstrates two phases of cell swelling during pyroptosis

May 3, 2024

Authors: Julien Nadjar, Sylvain Monnier, Estelle Bastien, Anne- Laure Huber, Christiane Oddou, Léa Bardoulet, Hubert B. Leloup, Gabriel Ichim, Christophe Vanbelle, Bénédicte F. Py, Olivier Destaing, Virginie Petrilli https://doi.org/10.1126/scisignal.abn8003, 2024  ...
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