Drug discovery Archives

Phenolic Fingerprinting and Bioactivity Profiling of Extracts and Isolated Compounds from Gypothamnium Pinifolium Phil.

Nov 28, 2022

Authors: Barrientos, R. E.; Ibáñez, E.; Puerta, A.; Padrón, J. M.; Paredes, A.; Cifuentes, F.; Romero-Parra, J.; Palacios, J.; Bórquez, J.; Simirgiotis, M. J. https://doi.org/10.3390/antiox11122313, 2022 Published in: Antioxidants Tags: Gypothamnium; phenolics; enzyme...

1,5-disubstituted-1,2,3-triazoles counteract mitochondrial dysfunction acting on F1FO-ATPase in models of cardiovascular diseases

Nov 24, 2022

Authors: Algieri, C.; Bernardini, C.; Marchi, S.; Forte, M.; Tallarida, M. A.; Bianchi, F.; La Mantia, D.; Algieri, V.; Stanzione, R.; Cotugno, M.; Costanzo, P.; Trombetti, F.; Maiuolo, L.; Forni, M.; De Nino, A.; Di Nonno, F.; Sciarretta, S.; Volpe, M.; Rubattu, S.;...

Blockade of Platelet CysLT1R Receptor with Zafirlukast Counteracts Platelet Protumoral Action and Prevents Breast Cancer Metastasis to Bone and Lung

Oct 17, 2022

Authors: Lou Saier; Johnny Ribeiro; Thomas Daunizeau; Audrey Houssin; Gabriel Ichim; Caroline Barette; Lamia Bouazza; Olivier Peyruchaud https://doi.org/10.3390/ijms232012221, 2022 Published in: International Journal of Molecular Sciences Tags: platelet; metastasis;...

Bioactive potential: a pharmacognostic definition through the screening of four Hypericum species from the Canary Islands

Oct 4, 2022

Authors: Rodney Lacret; Adrián Puerta; Sebastian Granica; Aday González-Bakker; Danela Hevia; Yiling Teng; Candelaria C. Sánchez-Mateo; Pedro Luis Pérez de Paz; José M. Padrón https://doi.org/10.3390/molecules27186101, 2022 Published in: Molecules Tags: Hypericum...

Preparation of a camptothecin analog FLQY2 self‑micelle solid dispersion with improved solubility and bioavailability

Sep 13, 2022

Authors: Yi Wang; Wenchao Wang; Endian Yu; Wenya Zhuang; Xuanrong Sun; Hong Wang; Qingyong Li https://doi.org/10.1186/s12951-022-01596-2, 2022 Published in: Journal of Nanobiotechnology Tags: Camptothecin, Soluplus®, Solid dispersion, Micelle, Solubility,...

« Older Entries

Next Entries »

Phenolic Fingerprinting and Bioactivity Profiling of Extracts and Isolated Compounds from Gypothamnium Pinifolium Phil.

1,5-disubstituted-1,2,3-triazoles counteract mitochondrial dysfunction acting on F1FO-ATPase in models of cardiovascular diseases

Blockade of Platelet CysLT1R Receptor with Zafirlukast Counteracts Platelet Protumoral Action and Prevents Breast Cancer Metastasis to Bone and Lung

Bioactive potential: a pharmacognostic definition through the screening of four Hypericum species from the Canary Islands

Preparation of a camptothecin analog FLQY2 self‑micelle solid dispersion with improved solubility and bioavailability

Recent Posts